Much attention is given to the study of generalized distributions because, adding more parameters gives flexibility in the shape, location, scale and tail(s) of a distribution. Existing literature shows that the generator approach is one of the desired methods of
constructing generalized distributions. Also, the mixture method is used because it gives flexibility to distributions.

Abstract Kinetoplastids are human pathogens with devastating economic and health effects, which include Leishmania and Trypanosoma species from flagellated protozoans. With the developed technology platform that allows the generation of high atomic level resolution of pathogen ribosome’s crystal structures, we demonstrate that rRNA is a target of choice for the development of next-generation drugs.

Many actuaries worldwide use Systematic Mortality Risk (SMR) to value actuarial prod-
ucts such as annuities and assurances sold to policyholders. Data availability plays an

essential role in ascertaining the SMR models’ accuracy, and it varies from one country to
another. Incorrect stochastic modeling of SMR models due to paucity of data has been a

problem for many Sub-Saharan African countries such as Kenya, thus prompting modifi-
cations of the classical SMR models used in those countries with limited data availability.